标准编号：ISO 21427-2:2006
中文名称：水质 通过微核诱变测量进行遗传毒性评估 第2部分：利用V79细胞系的混合种群法
英文名称：Water quality — Evaluation of genotoxicity by measurement of the induction of micronuclei — Part 2: Mixed population method using the cell line V79
发布日期：2006-11
标准范围
This part of ISO 21427 specifies a method for the determination of genotoxicity of water and waste water using a mammalian in vitro test which detects damage, induced by water-soluble substances, to the chromosomes or the mitotic apparatus of V79 cells from the Chinese hamster. The micronucleus test allows the identification of substances that cause cytogenetic damage which results in the formation of micronuclei containing lagging chromosome fragments and/or whole chromosomes. The assay is based on the increase in the frequency of micronucleated cells after incubation with and without metabolic activation.
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