标准编号:ISO 17099:2014

中文名称:放射防护 使用胞质分裂块在外周血淋巴细胞微核(CBMN)实验室测定生物剂量测定法的性能标准

英文名称:Radiological protection — Performance criteria for laboratories using the cytokinesis block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry

发布日期:2014-11

标准范围

This International Standard addresses the following:a) confidentiality of personal information for the customer and the laboratory;b) laboratory safety requirements;c) radiation sources, dose rates, and ranges used for establishing the calibration reference dose-effectcurves allowing the dose estimation from CBMN assay yields and the minimum resolvable dose;d) performance of blood collection, culturing, harvesting, and sample preparation for CBMN assay scoring;e) scoring criteria;f) conversion of micronucleus frequency in binucleated cells into an estimate of absorbed dose;g) reporting of results;h) quality assurance and quality control;i) informative annexes containing examples of a questionnaire, instructions for customers, amicroscope scoring data sheet, a sample report and advice on strengths and limitations of currentautomated systems for automated micronucleus scoring.

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