ISO 16640:2021 监测生产发射正电子的放射性核素和放射性药品的设施排出物中的放射性气体

标准编号：ISO 16640:2021

中文名称：监测生产发射正电子的放射性核素和放射性药品的设施排出物中的放射性气体

英文名称：Monitoring radioactive gases in effluents from facilities producing positron emitting radionuclides and radiopharmaceuticals

发布日期：2021-01

标准范围

This document focuses on monitoring the activity concentrations of radioactive gases. They allow the 
calculation of the activity releases, in the gaseous effluent discharge from facilities producing positron 
emitting radionuclides and radiopharmaceuticals. Such facilities produce short-lived radionuclides 
used for medical purposes or research and can release gases typically including, but not limited to ¹⁸F, 
 ¹¹C, ¹⁵O and ¹³N. These facilities include accelerators, radiopharmacies, hospitals and universities. This 
document provides performance-based criteria for the design and use of air monitoring equipment 
including probes, transport lines, sample monitoring instruments, and gas flow measuring methods. 
This document also provides information on monitoring program objectives, quality assurance, 
development of air monitoring control action levels, system optimisation and system performance 
verification.
The goal of achieving an unbiased measurement is accomplished either by direct (in-line) measurement 
on the exhaust stream or with samples extracted from the exhaust stream (bypass), provided that the 
radioactive gases are well mixed in the airstream. This document sets forth performance criteria and 
recommendations to assist in obtaining valid measurements.
NOTE 1 The criteria and recommendations of this document are aimed at monitoring which is conducted for 
regulatory compliance and system control. If existing air monitoring systems were not designed according to the 
performance criteria and recommendations of this document, an evaluation of the performance of the system 
is advised. If deficiencies are discovered based on a performance evaluation, a determination of the need for a 
system retrofit is to be made and corrective actions adopted where practicable.
NOTE 2 The criteria and recommendations of this document apply under both normal and off-normal 
operating conditions, provided that these conditions do not include production of aerosols or vapours. If the 
normal and/or off-normal conditions produce aerosols and vapours, then the aerosol collection principles of 
ISO 2889 also apply.

标准预览图