ISO 16000-39:2019 室内空气 第39部分：胺的测定 用（超）高效液相色谱-高分辨或串联质谱联用分析胺

标准编号：ISO 16000-39:2019

中文名称：室内空气 第39部分：胺的测定 用（超）高效液相色谱-高分辨或串联质谱联用分析胺

英文名称：Indoor air — Part 39: Determination of amines — Analysis of amines by (ultra-) high-performance liquid chromatography coupled to high resolution or tandem mass spectrometry

发布日期：2019-06

标准范围

This document, along with ISO 16000-38, specifies the measurement method for determining the mass 
concentration of primary, secondary and tertiary aliphatic and aromatic amines in indoor air using 
accumulated sampling and high-performance liquid chromatography (HPLC) coupled with tandem 
mass spectrometry (MS-MS) or high-resolution mass spectrometry (HRMS). The analytical procedure 
is covered by this document. The sampling procedure and the manufacturing of the samplers are 
covered by ISO 16000-38.
This document describes specifications for the chromatography and the mass spectroscopy for the 
amines. Measurement results are expressed in µg/m³ .
Although primarily intended for the measurement of amines listed in Tables A.1 and A.2, it can also be 
used for the measurement of other amines in indoor air. This document gives instructions and describes 
procedures for the inclusion of other amines.
The range of application of this document concerning the concentrations of amines in indoor air 
depends on the linear range of the calibration line and hence on the gas sample volume (here: from 5 l 
up to 100 l), the eluate volume (from 1 ml up to 5 ml), the injection volume (from 1 µl up to 10 µl) and 
the sensitivity of the analytical equipment (e.g. linear range from ² pg up to ² ng amine). The range 
of application can be expected to be from approximately 0,002 µg/m3(100 l sample) up to 2 000 µg/
m³ (5 l sample) for a common analytical equipment (e.g. Waters „TQD“) for the majority of the amines 
listed in Tables A.1 and A.2. The analysis of derivatives of ethanolamine is usually about 10 times more 
sensitive and the analysis of short-chained aliphatic amines is usually about 10 times less sensitive than 
the analysis of an average amine.
The performance data of the analytical method is given in Annex B, particularly in Tables B.1 and B.2.
This document can be used also for the determination of amines in water if the detection limit is 
sufficient.
This document does not cover the determination of isocyanates in indoor air (nor in water samples) as 
corresponding amines (covered by ISO 17734-1 and ISO 17734-2).

标准预览图